Free USMLE (United States Medical Licensing Examination) Exam Questions and Answers
The USMLE is a three-step sequence run jointly by the Federation of State Medical Boards and the National Board of Medical Examiners, and two things about it have changed recently enough to catch people out. Step 1 has reported pass or fail only — no number at all — for exams taken on or after 26 January 2022. And the block structure is changing mid-cycle in 2026: Step 2 CK moves to sixteen 30-minute blocks from 7 May and Step 1 to fourteen from 14 May, replacing the hour-long blocks both have used. Step 2 CK still returns a three-digit score, passing at 218, and Step 3 at 200 across its two days. Most boards require all three steps within seven years of your first pass, with four attempts allowed per step.
The first 10 questions on this page are free to read, answers included — no account and no card. A plan opens the rest of the bank, the full timed practice test and your weak-topic reporting.
Last updated: September 10, 2026
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- Medical and Health Licensing
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- First 10, with answers
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- 130 mins · 70%
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Question #1
A 65-year-old male presents with chest pain. ECG shows ST elevation in leads II, III, and aVF. What is the likely diagnosis?
Please select an optionIncorrectCorrect answer: A
ST elevation in inferior leads indicates an inferior MI, most likely due to occlusion of the right coronary artery.
Was this answer correct?Question #2
A patient with diabetes mellitus presents with a foot ulcer. What is the most important factor in its healing?
Please select an optionIncorrectCorrect answer: A
Maintaining tight blood glucose control is critical for wound healing in diabetic patients.
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A 40-year-old woman has sudden onset of severe headache and photophobia. What is the most likely diagnosis?
Please select an optionIncorrectCorrect answer: B
Sudden severe headache with photophobia is characteristic of subarachnoid hemorrhage.
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A patient with chronic kidney disease presents with fatigue and pallor. What is the most likely cause of these symptoms?
Please select an optionIncorrectCorrect answer: A
Chronic kidney disease often leads to anemia due to decreased erythropoietin production.
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A 70-year-old man presents with confusion and a history of falls. What is the most likely underlying cause?
Please select an optionIncorrectCorrect answer: D
The classic triad of normal pressure hydrocephalus includes confusion, gait disturbance, and urinary incontinence.
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A 25-year-old female presents with excessive thirst and urination. What condition should be ruled out?
Please select an optionIncorrectCorrect answer: B
The symptoms of polydipsia and polyuria are classic for diabetes mellitus, particularly type 1.
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A child presents with a rash, fever, and sore throat. What is the most likely diagnosis?
Please select an optionIncorrectCorrect answer: D
Scarlet fever, caused by Streptococcus pyogenes, presents with a characteristic rash following pharyngitis.
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A patient in a car accident presents with abdominal pain and signs of internal bleeding. What is the best initial diagnostic test?
Please select an optionIncorrectCorrect answer: C
Focused assessment with ultrasound for trauma (FAST) is the preferred initial test for internal bleeding.
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A 50-year-old male with a history of heavy alcohol use presents with confusion and ataxia. What is the most likely diagnosis?
Please select an optionIncorrectCorrect answer: C
Wernicke's encephalopathy is associated with thiamine deficiency, often seen in chronic alcoholics.
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A patient presents with recurrent episodes of abdominal pain and diarrhea. What is the most likely underlying condition?
Please select an optionIncorrectCorrect answer: A
Crohn's disease can present with recurrent abdominal pain and diarrhea due to inflammation of the gastrointestinal tract.
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FAQ
Learn More: https://www.gmc-uk.org/registration-and-licensing/join-our-registers/plab
- Q1: What is the USMLE (United States Medical Licensing Examination) exam?
- A: USMLE (United States Medical Licensing Examination) is a Medical and Health Licensing certification exam. Judging by the questions in our bank, it concentrates on presents, patient, condition, pain and diagnosis.
- Q2: What topics does the USMLE (United States Medical Licensing Examination) exam cover?
- A: Questions in our USMLE (United States Medical Licensing Examination) bank cluster around presents, patient, condition, pain, diagnosis, abdominal, fever and suspected. Working through the full set is the quickest way to find which of these you are weakest on.
- Q3: How should I prepare for USMLE (United States Medical Licensing Examination)?
- A: Work through the USMLE (United States Medical Licensing Examination) practice questions here, checking your answer on each one, then sit the practice test to rehearse the exam under timed conditions before the real thing.
- Q4: Are these real USMLE (United States Medical Licensing Examination) exam questions?
- A: They are drawn from officially released past questions and from community members who have sat USMLE (United States Medical Licensing Examination). Answers are verified and updated weekly.
- Q5: Where do I register for the USMLE (United States Medical Licensing Examination) exam?
- A: Register through Medical and Health Licensing directly at https://www.usmle.org/. Exampractice is not affiliated with Medical and Health Licensing and does not administer the exam.
- Q6: Is there a free USMLE (United States Medical Licensing Examination) sample?
- A: Yes. Every USMLE (United States Medical Licensing Examination) page shows a free sample of real questions. Upgrading opens the full bank and the practice test.