Free AQA GCSE Combined Science: Trilogy (8464) Exam Questions and Answers
AQA GCSE Combined Science: Trilogy (8464) is AQA's GCSE Combined Science: Trilogy qualification, specification 8464, taken in England. The questions here come from AQA's published question papers from June 2018 to June 2025, plus its specimen papers, with answers and marking guidance taken from AQA's own mark schemes. Written-answer questions let you work out your answer and then reveal what the mark scheme accepts; diagrams, graphs and source material appear with the questions that use them.
Candidates comparing AQA GCSE Combined Science: Trilogy (8464) exam dumps, ExamTopics and other practice tests use this page for the answers and explanations behind each question. Download the free PDF, then sit the timed exam simulation before booking with AQA.
Last updated: October 11, 2026
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Question #1
Figure 1 shows an animal cell. What is structure A?

Correct answer: A
Explanation
One mark for cell membrane. Extra boxes ticked cancels the mark.
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Question #2
Figure 1 shows an animal cell. What is structure B?

Correct answer: C
Explanation
One mark for nucleus. Extra boxes ticked cancels the mark.
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Question #3
Figure 2 shows a sperm cell. Describe how a sperm cell is adapted to carry out its function.

Type your answer, then reveal.
Correct answer: It has a tail so it can swim (to an egg).
Explanation
One mark. Also accept: it has many mitochondria to release energy to swim.
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Question #4
Figure 3 shows a scale drawing of one type of cell in blood. Use the scale to determine the width of the cell. Give your answer to the nearest micrometre. Width of cell = ____ micrometres

Type your answer, then reveal.
Correct answer: 8 micrometres
Explanation
One mark for 8 (micrometres).
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Question #5
Figure 3 shows a scale drawing of one type of cell in blood. Complete Table 1. Table 1 | Part of the blood | Function | | ____ | Carries oxygen around the body | | ____ | Protects the body against infection | | Plasma | ____ |


Type your answer, then reveal.
Correct answer: Red blood cell(s) carry oxygen; white blood cell(s) protect against infection; plasma transports proteins / dissolved substances / food molecules / urea / hormones / blood cells.
Explanation
One mark each. Red blood cell(s); white blood cell(s) (a named cell is accepted, e.g. phagocyte or lymphocyte); plasma function: transports proteins, dissolved substances, food (molecules), urea, hormones or blood cells.
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Question #6
Figure 3 shows a scale drawing of one type of cell in blood. Platelets are fragments of cells. Platelets help the blood to clot. Suggest what might happen if the blood did not clot.

Type your answer, then reveal.
Correct answer: You could lose a lot of blood / bleed internally.
Explanation
Any one from: you could lose a lot of blood; bleed internally. Also allow: bleeding would not stop; could bleed to death.
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Question #7
Respiration can happen aerobically or anaerobically. Respiration transfers energy from glucose. Table 2 shows the amount of energy released by aerobic and anaerobic respiration. Suggest why human cells might respire anaerobically, even though only a small amount of energy is transferred.

Type your answer, then reveal.
Correct answer: Not enough oxygen is present for aerobic respiration, or more energy is needed for exercise than aerobic respiration can transfer.
Explanation
Any one from: not enough oxygen present (for aerobic respiration); more energy required for exercise (than can be transferred by aerobic respiration). A named example of exercise is allowed.
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Question #8
Respiration can happen aerobically or anaerobically. Respiration transfers energy from glucose. Yeast is used in the brewing and baking industries. Why is yeast used in these industries?
Type your answer, then reveal.
Correct answer: Yeast respires anaerobically (fermentation) and produces carbon dioxide and ethanol. Carbon dioxide makes bread rise and makes beer, cider or some wines fizzy. Ethanol is the alcohol in beer, cider, wine or spirits.
Explanation
One mark for produces carbon dioxide. One mark for produces ethanol. Plus any two from: carbon dioxide makes bread rise; carbon dioxide makes beer / cider / (some) wines fizzy; ethanol is the alcohol in beer / cider / wine / spirits. Allow 'for alcoholic drinks' or a named drink.
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Question #9
Some students investigated how exercise affects heart rate. Figure 4 shows their results. What was Student B's resting heart rate? Resting heart rate = ____ beats per minute

Type your answer, then reveal.
Correct answer: 66 beats per minute
Explanation
One mark for 66.
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Question #10
Some students investigated how exercise affects heart rate. Figure 4 shows their results. The students started running at 2 minutes. What evidence for this is in Figure 4?

Type your answer, then reveal.
Correct answer: Heart rate increased (at 2 minutes)
Explanation
One mark for stating that heart rate increased.
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