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Free U.S. National Institutes of Health (NIH) Clinical Research Coordinator Exam Exam Questions and Answers
Last updated: March 31, 2025
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U.S. National Institutes of
Health (NIH) Clinical Research Coordinator Exam
#Question
What must a Clinical Research Coordinator do when a participant expresses dissatisfaction with the study?
A.
Document the concern and discuss it with the investigator
B.
Change the study protocol immediately
C.
Ignore the feedback
D.
Ask the participant to leave
Correct Answer:
A
The CRC should document the participant's concern and discuss it with the investigator to address any issues and improve participant experience.
#Question
What is the purpose of participant randomization in a clinical trial?
A.
To increase participant diversity
B.
To ensure equal treatment distribution
C.
To prevent bias in treatment assignment
D.
To simplify data analysis
Correct Answer:
C
Participant randomization in a clinical trial prevents bias in treatment assignments, ensuring that results are valid and reliable.
#Question
In clinical trials, what is the significance of conducting a pre-study site visit?
A.
To assess site readiness and resources
B.
To review financial statements
C.
To train study staff
D.
To finalize participant recruitment
Correct Answer:
A
A pre-study site visit assesses the siteÕs readiness and resources to conduct the trial effectively, ensuring compliance with study requirements.
#Question
What should a Clinical Research Coordinator do if a participant experiences a change in their medical condition during the trial?
A.
Allow the participant to continue without concern
B.
Document the change and notify the investigator
C.
Ignore the change
D.
Wait for the next monitoring visit
Correct Answer:
B
The CRC should document the change in the participant's medical condition and notify the investigator to ensure proper monitoring and safety.
#Question
What is the role of informed consent in protecting vulnerable populations?
A.
It ensures they understand their rights and the study details
B.
It guarantees recruitment
C.
It is less important for vulnerable populations
D.
It protects their financial interests
Correct Answer:
A
Informed consent plays a critical role in protecting vulnerable populations by ensuring they understand their rights and the details of the study before participation.
#Question
How can a Clinical Research Coordinator ensure compliance with the study protocol?
A.
By conducting random checks only
B.
By relying on verbal instructions
C.
By keeping detailed and accurate records
D.
By minimizing communication with the study team
Correct Answer:
C
Ensuring compliance involves keeping detailed and accurate records of all study-related activities to demonstrate adherence to the protocol.
#Question
What is the purpose of conducting a risk-benefit analysis in clinical trials?
A.
To evaluate recruitment strategies
B.
To determine participant demographics
C.
To finalize the study budget
D.
To assess the ethical justification of the study
Correct Answer:
D
A risk-benefit analysis assesses the ethical justification of conducting the study by weighing potential risks against expected benefits to participants.
U.S. National Institutes of Health (NIH) Clinical Research Coordinator Exam
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